“Assessing glycosylation of ANCA in ANCA-Associated Vasculitis” by: Dr. Zach Wallace (MGH)
“The Lupus Patient Journey – Onset, Outcomes, and Opportunities” by: Dr. May Choi (BWH)
Location: Zoom
Time: 12:30-1:30 p.m.
February 18th
“Mechanisms of T cell co-stimulation: the role of the volume-regulated anion channel subunit LRRC8A in T cell-driven diseases” by: Dr. Janet Chou (BCH)
“Bedside to single-cell to bench: Inflammatory pulmonary fibrosis & RA-ILD” by: Dr. Edy Kim (BWH)
Location: Zoom
Time: 12:30-1:30 p.m.
January 21st
“Adipose tissue as a storage bank for arthritogenic T cells” by: Dr. Heather Faust (BWH)
“Multi-omic exploration of Still’s disease and Macrophage Activation Syndrome” (including discussion of OLINK as a potential new JBC service) by: Dr. Pui Lee (BCH)
Location: Zoom
Time: 12:30-1:30 p.m.
2021
December 17th
MGH Personalized Medicine by: Dr. Beth Karlson (BWH)
“Overexpression of Pericyte and mural HIF2a Exacerbates Hypoxia-induced Pulmonary Hypertension and Right Ventricular Hypertrophy” by: Dr. Ke Yuan (BCH)
Location: Zoom
Time: 12:30-1:30 p.m.
November 29th
Cardiovascular events in patients with calcium pyrophosphate deposition (CPPD) disease: do traditional risk factors explain it all? by: Dr. Sara Tedeschi (BWH)
The joint-specific memory of arthritis flares by: Dr. Margaret Chang (BCH)
Location: Zoom
Time: 12:30-1:30 p.m.
October 29th
RA-related lung disease by: Greg McDermott (BWH)
CATCH mentoring program by: Elsa Treffeisen & Mia Chandler (BCH)
Treatment of MIS-C: What have we learned? by Dr. Mary Beth Son
Complement regulator properdin: Is oligomer distribution and function altered in disease? by Dr. Viviana Ferreira
Location: Zoom
Time: 12:30-1:30 p.m.
May 28th
Regulating MDA5 to restrain aberrant innate immune activation by Dr. Tiffany Hsu
Type III interferons: friends or foes at mucosal barriers? by Dr. Ivan Zanoni
Location: Zoom
Time: 12:30-1:30 p.m.
April 30th
Stromal Wnt Activity and Function in Chronic Inflammatory Statesby Dr. Alisa Mueller
Noninvasive ultrasound of the spleen to treat inflammatory diseases by Dr. Bryce Binstadt
Location: Zoom
Time: 12:30-1:30 p.m.
March 26th
Immune Checkpoint Inhibitor Treatment in Cancer: Immunomodulator Use and Evaluation by Rheumatology by Dr. Kiki Cunningham-Bussel
Cell-mediated cytotoxicity in Lyme arthritis by Dr. Allen Steere
Location: Zoom
Time: 12:30-1:30 p.m.
February 26th
Rheumatoid arthritis studies using the Mass General Brigham Biobank by Dr. Jeffrey Sparks
From bedside to benchtop: reverse translational approaches to studying kidney macrophages in lupus nephritis by Dr. Paul Hoover
Location: Zoom
Time: 12:30-1:30 p.m.
January 29th
JBC 2021: New synergies with the Boston Children’s Hospital Division of Immunology by Dr. Peter Nigrovic
What’s in a cell? Vectors of immune cell heterogeneity by Dr. Ricardo Grieshaber-Bouyer
Location: Zoom
Time: 12:30-1:30 p.m.
2020
December 20th
Intrinsic roles of citrullination in health and disease by Dr. I-Cheng Ho
Serologic diagnosis of Lyme disease in Pedi Lyme Net by Dr. Lise Nigrovic and Felix Radtke
Location: Zoom
Time: 12:30-1:30 p.m.
November 20th
Epidemiologic Clues to the Etiology of SLE by Dr. Karen Costenbader
Immunophenotyping as an ‘immune function test by Dr. Deepak Rao
Location: Zoom
Time: 12:30-1:30 p.m.
October 30th
Osteoarthritis and Inflammation by Dr. Lindsey Macfarlane
From genetic sequences to bDMARD sequences by Dr. Katherine Liao
Location: Zoom
Time: 12:30-1:30 p.m.
September 18th
Steps toward understanding human axial spondyloarthritis by Dr. Joerg Ermann
Phenotyping and studying heart failure in rheumatoid arthritis patients in the EHR by Dr. Selena Huang
Location: Zoom
Time: 12:30-1:30 p.m.
June 26th
Using CRISPR-Cas Technologies to Investigate the Genetics of Autoimmune Diseases by Yuriy Baglaenko
TARGET: An RCT in RA with Great Biospecimens by Dr. Daniel Solomon
Location: Zoom
Time: 12:30-1:30 p.m.
May 22nd
Cellular heterogeneity and lineage restriction during mouse digit tip regeneration by Dr. Jessica Lehoczky
How many kinds of neutrophils are there? by Ricardo Grieshaber
Location: Zoom
Time: 12:30-1:30 p.m.
April 17th
The COPPAR program by Dr. Joseph Merola and Dr. Nancy Shadick
Projects relating to OA and meniscal tear by Dr. Jeffrey Katz
Location: Zoom
Time: 12:30-1:30 p.m.
January 31st
The role of the intracellular DNA sensor STING in bone homeostasis by Dr. Susan MacLauchlan
What inter-individual differences in T cell activation can tell us about autoimmune disease mechanisms by Dr. Maria Gutierrez-Archelus
Location: Marshall A. Wolfe Conference Room, 60 Fenwood Rd, Boston, MA 02115
Time: 12:30-1:30 p.m.
2019
December 20th
Natural killer cell functions from a rheumatological perspective by Dr. Wolfgang Merkt
Novel anti-fibrotic therapies for Systemic Sclerosis by Dr. David Lagares
Location: Marshall A. Wolfe Conference Room, 60 Fenwood Rd, Boston, MA 02115
Time: 12:30-1:30 p.m.
November 22nd
Stability of the CD4 T Cell Receptor β chain (TCRB) Repertoire in the Joints of Oligoarticular Juvenile Idiopathic Arthritis Patients by Dr. Amelie Jule
Revisiting the Safety of Methotrexate: Update Based on Data From the CIRT Trial by Dr. Elizabeth Karlson
Location: Marshall A. Wolfe Conference Room, 60 Fenwood Rd, Boston, MA 02115
Time: 12:30-1:30 p.m.
October 25th
JBC Year 4 by Dr. Peter Nigrovic
Single cell transcriptomic and proteomic profiling of lung and synovium in rheumatoid arthritis by Drs. Kevin Wei and Fan Zhang
Location: Bayles Conference Room, 15 Francis Street, Boston, MA 02115
Time: 12:30-1:30 p.m.
March 22nd
CyTOF analyses of knowns and unknown by Dr. Deepak Rao
Gut microbiota, IGF-1 and Skeletal Growth by Dr. Julia Charles
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
February 15th
Physiological and Pathological Roles of Protein Citrullination by I-Cheng Ho
Grant Aims 2018 by Dr. Lindsey Macfarlane
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
January 25th
Finding mediators of the response to TNF and IL-17: RNA-seq with time-series, dose-response, and gene silencing by Kamil Slowikowski
Biomarkers and Genetics of Rheumatoid Arthritis-associated Interstitial Lung Disease by Dr. Tracy Doyle
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
2018
December 21st
AERD- Aspirin-Exacerbated Respiratory Disease by Dr. Tanya Laidlaw
Leveraging Cytometry by Time of Flight Technology: Analyzing murine bone marrow in neutropenic sepsis by Dr. Julie Ng
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
November 30th
The Childhood Arthritis & Rheumatology Research Alliance by Dr. Mary Beth Son
Deficiency of adenosine deaminase 2 (DADA2)- Monogenic vasculitis and beyond by Dr. Pui Lee
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
September 28
RNA sequencing of monocyte subsets from blood and synovial fluid by Dr. Daimon Simmons
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
May 25th
Software for Quantitative Image Assessment of Musculoskeletal Diseases: A Tasting Menu of Methodologies by Dr. Jeffrey Duryea
All of Us Research Program by Dr. Elizabeth Karlson
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Studies of At-Risk Populations Provide Insights into the Origins and Pathogenesis of Pre-Clinical Rheumatoid Arthritis
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
Patient Care Rounds
Are We Ready for Prevention of Rheumatoid Arthritis?
Location: Room 5010- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
April 28th
Exploration of myeloid cell biology using Hoxb8 cells. by Dr. Pui Lee
Translational Research using Patient Samples and Data by Dr. Yvonne Lee
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
February 17th
Introduction to Boston Children’s Hospital Biorepositories by Dr. Lauren Henderson
RNAseq-driven differentiation of neutrophil subsets defined via CD177 by Ricardo Grieshaber
Location: Room 02006B- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
January
Introduction to RNA-sew by Dr. Chad Nusbaum
Application of RNA sequencing in RA research and Data Analysis by Dr. Kevin Wei and Kamil Slowikowski
Location: Room 3014- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
2016
December
Using the Partners Biobank Portal for research studies by Dr. Elizabeth Karlson
Clinical research tools using the electronic medical record: natural language processing (NLP) and phenome-wide association study (PheWAS) By Dr. Jeffrey Sparks
Location: Room 6014- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
October
JBC Updates by Dr. Peter Nigrovic
Introduction to CyTOF by Dr. Jim Lederer
CyTOF Application in Research by Dr. Deepak Rao
Location: Room 3014- Building of Transformative Medicine (BTM), 60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.
September
Introducing the NIAMS-funded Joint Biology Consortium (JBC) by Drs. Peter Nigrovic and Elizabeth Karlson
Location: Room 546- Large Conference Room, Smith Building, 1 Jimmy Fund Way, Boston, MA 02115
